PRIMARY STUDY
Role of Cannabinoids in Gastrointestinal Mucosal Defense and Inflammation
Key Findings: This review highlights that direct or indirect modulation of the endocannabinoid system, particularly through CB1 and CB2 receptor activation and inhibition of endocannabinoid-degrading enzymes, exerts gastroprotective, anti-inflammatory, and motility-regulating effects, supporting its therapeutic potential in gastrointestinal injury and inflammatory bowel diseases.
Type of Study: Clinical Meta-analysis
Study Result: Positive
Research Location(s): Hungary
Year of Pub: 2026
Cannabinoids Studied: Cannabinoid (unspecified)
Phytocannabinoid Source: Not Applicable
Receptors Studied: CB1, CB2
Route of Administration: , In vitro, Injection
Citation: Gyires K, Zádori ZS. Role of Cannabinoids in Gastrointestinal Mucosal Defense and Inflammation. Curr Neuropharmacol. 2016;14(8):935-951. doi: 10.2174/1570159x14666160303110150. PMID: 26935536; PMCID: PMC5333598.
