PRIMARY STUDY
Cannabinoids and gastrointestinal motility: animal and human studies
Key Findings: This review highlights that the endogenous cannabinoid system, through CB1- and CB2-mediated modulation of enteric neurotransmission, inflammation, and motility, plays a key role in gastrointestinal function and represents a promising therapeutic target for disorders of gut motility and inflammatory gastrointestinal diseases.
Type of Study: Meta-analysis
Study Result: Positive
Research Location(s): Italy
Year of Pub: 2026
Cannabinoids Studied: Tetrahydrocannabinol (THC)
Phytocannabinoid Source: Not Applicable
Chemotype: , Chemotype I
Receptors Studied: CB1, CB2
Citation: Aviello G, Romano B, Izzo AA. Cannabinoids and gastrointestinal motility: animal and human studies. Eur Rev Med Pharmacol Sci. 2008 Aug;12 Suppl 1:81-93. PMID: 18924447.
