RELATED STUDY
Therapeutic Potential of Cannabinoid Receptors Type 1 and 2-Novel Insights for Enhancing the Chance of Clinical Success
Key Findings: This review, comprising eight original articles and three reviews, emphasizes the potential of the endocannabinoid system (ECS) modulation to revolutionize therapeutic strategies in a wide range of human conditions and lays a foundation for future research and clinical application.
Type of Study: Meta-analysis
Study Sample Size: 11
Study Result: Positive
Research Location(s): Sweden
Year of Pub: 2025
Cannabinoids Studied: Cannabidiol (CBD), Tetrahydrocannabinol (THC), Cannabigerolic Acid (CBG-a), Tetrahydrocannabinolic Acid (THC-a), CP-x Synthetic Cannabinoids, HU-x Synthetic Cannabinoids, Anandamide (AEA), 2-Arachidonoyl Glycerol (2-AG), Synthetic Cannabinoid (unspecified), Endocannabinoid (unspecified)
Phytocannabinoid Source: Not Applicable
Chemotype: Chemotype I, Chemotype III
Receptors Studied: CB1, CB2, GPCR
Ligands Studied: Pro-inflammatory cytokines
Citation: Grether U. Therapeutic Potential of Cannabinoid Receptors Type 1 and 2-Novel Insights for Enhancing the Chance of Clinical Success. Pharmaceuticals (Basel). 2025 Sep 4;18(9):1324. doi: 10.3390/ph18091324. PMID: 41011195; PMCID: PMC12473137.
