PRIMARY STUDY

Immunomodulation by cannabinoids: Current uses, mechanisms, and identification of data gaps to be addressed for additional therapeutic application

Key Findings:  This review summarizes preclinical and clinical evidence supporting the immunomodulatory potential of cannabinoids and cannabinoid-based therapeutics targeting CB1 and CB2 receptors in immune-mediated diseases, highlighting key findings, genetic insights, and critical data gaps for future research.

Type of Study:  Clinical Meta-analysis

Study Result:  Positive

Research Location(s):  United States

Year of Pub:  2025


Cannabinoids Studied:  Cannabinoid (unspecified)

Phytocannabinoid Source:  Not Applicable

Receptors Studied:  CB1, CB2




Citation:  Kaminski NE, Kaplan BLF. Immunomodulation by cannabinoids: Current uses, mechanisms, and identification of data gaps to be addressed for additional therapeutic application. Adv Pharmacol. 2021;91:1-59. doi: 10.1016/bs.apha.2021.01.001. Epub 2021 Mar 12. PMID: 34099105.