PRIMARY STUDY
Cannabidiol: Influence on B Cells, Peripheral Blood Mononuclear Cells, and Peripheral Blood Mononuclear Cell/Rheumatoid Arthritis Synovial Fibroblast Cocultures
Key Findings: Cannabidiol (CBD) has both pro- and anti-inflammatory effects in isolated B cells and peripheral blood mononuclear cells (PBMCs), and this study concluded that CBD might be used to lessen B cell activity in rheumatoid arthritis, and other auto-immune conditions.
Type of Study: Laboratory Study
Study Result: Positive
Research Location(s): Germany
Year of Pub: 2022
Cannabinoids Studied: Cannabidiol (CBD)
Phytocannabinoid Source: Unspecified
Chemotype: Chemotype III
Receptors Studied: CB1, CB2, TRPA1
Ligands Studied: Anti-inflammatory cytokines, Pro-inflammatory cytokines
Citation: Lowin T, et al. Cannabidiol: Influence on B Cells, Peripheral Blood Mononuclear Cells, and Peripheral Blood Mononuclear Cell/Rheumatoid Arthritis Synovial Fibroblast Cocultures. Cannabis Cannabinoid Res. 2023; 8:321-334. doi: 10.1089/can.2021.0241
Authors: Lowin T, Laaser SA, Kok C, Bruneau E, Pongratz G
