PRIMARY STUDY
Experimental Cannabinoid 2 Receptor-Mediated Immune Modulation in Sepsis.
Key Findings: Using various compounds we have shown different mechanisms of activating CB2 receptors to reduce leukocyte endothelial interactions in order to prevent further inflammatory damage during sepsis.
Type of Study: Animal Study
Study Result: Positive
Research Location(s): Canada
Year of Pub: 2014
Cannabinoids Studied: AM-x Synthetic Cannabinoids, HU-x Synthetic Cannabinoids, Fatty Acid Amide Hydrolase (FAAH), Monoacylglycerol Lipase (MAGL)
Phytocannabinoid Source: Not Applicable
Receptors Studied: CB2
Citation: Sardinha J, et al. Experimental cannabinoid 2 receptor-mediated immune modulation in sepsis. Mediators Inflamm. 2014; 2014:978678. doi: 10.1155/2014/978678
Authors: Sardinha J, Kelly ME, Zhou J, Lehmann C
