PRIMARY STUDY
Simultaneous measurement of anandamide and 2-arachidonoylglycerol by polymyxin B-selective adsorption and subsequent high-performance liquid chromatography analysis: increase in endogenous cannabinoids in the sera of patients with endotoxic shock
Key Findings: Researchers discovered higher level of anandamide and 2-AG in patients with endotoxic shock than in healthy persons. This finding suggest a role of these endogenous cannabinoids in the development of hypotension secondary to human endotoxic shock.
Type of Study: Meta-analysis
Study Result: Inconclusive
Research Location(s): Japan
Year of Pub: 2001
Cannabinoids Studied: Anandamide (AEA), 2-Arachidonoyl Glycerol (2-AG)
Phytocannabinoid Source: Not Applicable
Citation: Wang Y, et al. Simultaneous measurement of anandamide and 2-arachidonoylglycerol by polymyxin B-selective adsorption and subsequent high-performance liquid chromatography analysis: increase in endogenous cannabinoids in the sera of patients with endotoxic shock. Anal Biochem. 2001; 294:73-82. doi: 10.1006/abio.2001.5015
Authors: Wang Y, Liu Y, Ito Y, Hashiguchi T, Kitajima I, Yamakuchi M, Shimizu H, Matsuo S, Imaizumi H, Maruyama I
