PRIMARY STUDY

Clozapine use in patients with schizophrenia and a comorbid substance use disorder: A systematic review

Key Findings:  This systematic review on the efficacy of clozapine in SUD improvement in schizophrenic patients found that for poly-substance and cannabis users clozapine was superior to risperidone but equal to olanzapine or ziprasidone.

Type of Study:  Meta-analysis

Study Sample Size:  14

Study Result:  Positive

Research Location(s):  Spain

Year of Pub:  2018


Cannabinoids Studied:  Cannabinoid (unspecified)

Phytocannabinoid Source:  Not Applicable




Citation:  Arranz B, et al. Clozapine use in patients with schizophrenia and a comorbid substance use disorder: A systematic review. Eur Neuropsychopharmacol. 2018; 28:227-242. doi: 10.1016/j.euroneuro.2017.12.006

Authors:  Arranz B, Garriga M, García-Rizo C, San L