PRIMARY STUDY

The brain effects of cannabis in healthy adolescents and in adolescents with schizophrenia: a systematic review

Key Findings:  This review of the impact of cannabis on adolescent brain development indicates that cannabis use may exacerbate memory loss and hippocampal volume changes in healthy adolescents and potentially contribute to more extensive gray and white matter changes in adolescent-onset schizophrenia, with a need for more robust, longitudinal studies to clarify these associations.