PRIMARY STUDY

Impact of cannabis use and its cessation on the dosage and the efficacy of antipsychotic drugs in in- and outpatients with schizophrenia taking medication: A systematic review and meta-analysis

Key Findings:  Cannabis use did not affect the efficacy of antipsychotics, symptoms evolution, or higher rate of antipsychotic resistance in subjects with schizophrenia. Cannabis use was linked to a higher risk of relapse.

Type of Study:  Clinical Meta-analysis

Study Sample Size:  12

Study Result:  Inconclusive

Research Location(s):  France, Netherlands

Year of Pub:  2022


Cannabinoids Studied:  Cannabinoid (unspecified)

Phytocannabinoid Source:  Not Applicable




Citation:  Rault O, et al. Impact of cannabis use and its cessation on the dosage and the efficacy of antipsychotic drugs in in- and outpatients with schizophrenia taking medication: A systematic review and meta-analysis. J Psychiatr Res. 2022; 156:713-721. doi: 10.1016/j.jpsychires.2022.11.012

Authors:  Rault O, Romeo B, Butlen-Ducuing F, Rari E, Benyamina A, Martelli C