PRIMARY STUDY
Improved Social Interaction, Recognition and Working Memory with Cannabidiol Treatment in a Prenatal Infection (poly I:C) Rat Model.
Key Findings: Chronic CBD administration can attenuate the social interaction and cognitive deficits induced by prenatal poly I:C infection. These novel findings present interesting implications for potential use of CBD in treating the cognitive deficits and social withdrawal of schizophrenia.
Type of Study: Animal Study
Study Result: Positive
Research Location(s): Australia
Year of Pub: 2017
Cannabinoids Studied: Cannabidiol (CBD)
Chemotype: Chemotype III
Ligands Studied: Dopamine, GABA, Glutamate
Dosage: CBD (10 mg/kg) dissolved in Tween 80 or saline (vehicle)
Route of Administration: Injection
Citation: Osborne AL, et al. Improved Social Interaction, Recognition and Working Memory with Cannabidiol Treatment in a Prenatal Infection (poly I:C) Rat Model. Neuropsychopharmacology. 2017; 42:1447-1457. doi: 10.1038/npp.2017.40
Authors: Osborne AL, Solowij N, Babic I, Huang XF, Weston-Green K
