Key Findings:  It is now incontrovertible that heavy use of cannabis increases the risk of psychosis. There is a dose-response relationship and high potency preparations and synthetic cannabinoids carry the greatest risk. CBD appears to counteract Δ9-THC-induced psychotic symptoms and cognitive impairment, and may even have antipsychotic properties.
Type of Study:  Meta-analysis
Study Result:  Negative
Research Location(s):  Belgium, Germany, Hungary, Italy, Japan, United Kingdom
Year of Pub:  2018
Cannabinoids Studied:  Cannabidiol (CBD), Cannabinoid (unspecified), Synthetic Cannabinoid (unspecified)
Phytocannabinoid Source:  Not Applicable
Chemotype:  Chemotype I, Chemotype III
Citation:  Colizzi M and Murray R. Cannabis and psychosis: what do we know and what should we do?. Br J Psychiatry. 2018; 212:195-196. doi: 10.1192/bjp.2018.1
Authors:  Colizzi M, Murray R