Key Findings:  This study examined the effects of nicotine in on cannabis users and the risk of developing psychotic and cognitive impairments. They concluded that there was no difference in sensory gating with nicotine compared to placebo cannabis, and acute nicotine administration did not appear to impact sensory gating function. There is a relationship between cannabis use and gating impairment.
Type of Study:  Double Blind Clinical Trial
Study Sample Size:  43
Study Result:  Inconclusive
Research Location(s):  Canada
Year of Pub:  2021
Cannabinoids Studied:  Cannabinoid (unspecified)
Phytocannabinoid Source:  Not Applicable
Citation:  Francis AM, et al. Sensory gating in tobacco-naïve cannabis users is unaffected by acute nicotine administration. Psychopharmacology (Berl). 2022; 239:1279-1288. doi: 10.1007/s00213-021-05843-6
Authors:  Francis AM, Parks A, Choueiry J, El-Marj N, Impey D, Knott VJ, Fisher DJ