PRIMARY STUDY

Cannabidiol and Amisulpride Improve Cognition in Acute Schizophrenia in an Explorative, Double-Blind, Active-Controlled, Randomized Clinical Trial

Key Findings:  Cannabidiol (CBD) and amisulpride (AMI) (an antiemetic and antipsychotic medication) both improved neurocognitive functioning independently and with similar efficacy in patients with acute schizophrenia.

Type of Study:  Double Blind Clinical Trial

Study Sample Size:  42

Study Result:  Positive

Research Location(s):  Australia, Germany

Year of Pub:  2021


Cannabinoids Studied:  Cannabidiol (CBD), Anandamide (AEA)

Phytocannabinoid Source:  Unspecified

Chemotype:  Chemotype III

Dosage: CBD (800 mg/day)

Route of Administration:  Oral (Ingestion)




Citation:  Leweke FM, et al. Cannabidiol and Amisulpride Improve Cognition in Acute Schizophrenia in an Explorative, Double-Blind, Active-Controlled, Randomized Clinical Trial. Front Pharmacol. 2021; 12:614811. doi: 10.3389/fphar.2021.614811

Authors:  Leweke FM, Rohleder C, Gerth CW, Hellmich M, Pukrop R, Koethe D