PRIMARY STUDY

Cannabidiol: A Potential New Alternative for the Treatment of Anxiety, Depression, and Psychotic Disorders

Key Findings:  Animal trials suggest that the effects of CBD depend on dose, strain, can vary in acute and chronic setting, and with different form of administration. CBD is posited to induce its effects via CB1, CB2, 5-HT1A receptor sites and neurogenesis factors. Early clinical trials support the efficacy of CBD as an anxiolytic, antipsychotic, and antidepressant, and a positive risk-benefit profile.

Type of Study:  Meta-analysis

Study Result:  Positive

Research Location(s):  Spain

Year of Pub:  2020


Cannabinoids Studied:  Cannabidiol (CBD)

Phytocannabinoid Source:  Unspecified

Chemotype:  Chemotype III

Receptors Studied:  CB1, CB2

Ligands Studied:  Serotonin




Citation:  García-Gutiérrez MS, et al. Cannabidiol: A Potential New Alternative for the Treatment of Anxiety, Depression, and Psychotic Disorders. Biomolecules. 2020; 10:(unknown pages). doi: 10.3390/biom10111575

Authors:  García-Gutiérrez MS, Navarrete F, Gasparyan A, Austrich-Olivares A, Sala F, Manzanares J