PRIMARY STUDY

Measuring Disturbance of the Endocannabinoid System in Psychosis A Systematic Review and Meta-analysis

Key Findings:  The reviewers noticed an increased endocannabinoid tone in psychotic patients which was inversely associated with the severity of psychosis symptoms and which normalized after remission of psychosis and as such may suggest a novel target for illness indicator measurement and treatment.

Type of Study:  Meta-analysis

Study Result:  Inconclusive

Research Location(s):  Italy, United States

Year of Pub:  2019


Cannabinoids Studied:  Endocannabinoid (unspecified)

Phytocannabinoid Source:  Not Applicable




Citation:  Minichino A, et al. Measuring Disturbance of the Endocannabinoid System in Psychosis: A Systematic Review and Meta-analysis. JAMA Psychiatry. 2019; 76:914-923. doi: 10.1001/jamapsychiatry.2019.0970

Authors:  Minichino A, Senior M, Brondino N, Zhang SH, Godwlewska BR, Burnet PWJ, Cipriani A, Lennox BR