Key Findings:  The reviewers noticed an increased endocannabinoid tone in psychotic patients which was inversely associated with the severity of psychosis symptoms and which normalized after remission of psychosis and as such may suggest a novel target for illness indicator measurement and treatment.
Type of Study:  Meta-analysis
Study Result:  Inconclusive
Research Location(s):  Italy, United States
Year of Pub:  2019
Cannabinoids Studied:  Endocannabinoid (unspecified)
Phytocannabinoid Source:  Not Applicable
Citation:  Minichino A, et al. Measuring Disturbance of the Endocannabinoid System in Psychosis: A Systematic Review and Meta-analysis. JAMA Psychiatry. 2019; 76:914-923. doi: 10.1001/jamapsychiatry.2019.0970
Authors:  Minichino A, Senior M, Brondino N, Zhang SH, Godwlewska BR, Burnet PWJ, Cipriani A, Lennox BR