PRIMARY STUDY

Different temporal windows for CB1 receptor involvement in contextual fear memory destabilisation in the amygdala and hippocampus

Key Findings:  This study demonstrates that the temporal windows for CB1 receptor-mediated memory destabilization during reconsolidation differ between the hippocampus and amygdala, suggesting variations in the timing or role of CB1 receptors across these brain structures.

Type of Study:  Animal Study

Study Result:  Negative

Research Location(s):  Brazil

Year of Pub:  2019


Cannabinoids Studied:  SR-x Synthetic Cannabinoids

Phytocannabinoid Source:  Not Applicable

Receptors Studied:  CB1, CB1 antagonist




Citation:  Lee JLC, et al. Different temporal windows for CB1 receptor involvement in contextual fear memory destabilisation in the amygdala and hippocampus. PLoS One. 2019; 14:e0205781. doi: 10.1371/journal.pone.0205781

Authors:  Lee JLC, Amorim FE, Cassini LF, Amaral OB