Key Findings: Researchers propose that a state of endocannabinoid deficiency could represent a stress susceptibility endophenotype predisposing to the development of trauma-related psychopathology and provide biologically plausible support for the self-medication hypotheses used to explain high rates of cannabis use in patients with trauma-related disorders.
Type of Study: Meta-analysis
Study Result: Positive
Research Location(s): Canada, Italy, United States
Year of Pub: 2018
Cannabinoids Studied: Cannabinoid (unspecified), Endocannabinoid (unspecified)
Phytocannabinoid Source: Not Applicable
Citation: Hill MN, et al. Integrating Endocannabinoid Signaling and Cannabinoids into the Biology and Treatment of Posttraumatic Stress Disorder. Neuropsychopharmacology. 2018; 43:80-102. doi: 10.1038/npp.2017.162
Authors: Hill MN, Campolongo P, Yehuda R, Patel S