PRIMARY STUDY

The effects of MDMA-assisted therapy on alcohol and substance use in a phase 3 trial for treatment of severe PTSD

Key Findings:  MDMA-assisted therapy had a greater reduction in Alcohol Use Disorder Identification Test scores than placebo, but no difference in scores for the Drug Use Disorder Identification Test in MDMA-assisted versus placebo therapy.

Type of Study:  Double Blind Clinical Trial

Study Sample Size:  90

Study Result:  Positive

Research Location(s):  United States

Year of Pub:  2022


Cannabinoids Studied:  Cannabinoid (unspecified)

Phytocannabinoid Source:  Unspecified




Citation:  Nicholas CR, et al. The effects of MDMA-assisted therapy on alcohol and substance use in a phase 3 trial for treatment of severe PTSD. Drug Alcohol Depend. 2022; 233:109356. doi: 10.1016/j.drugalcdep.2022.109356

Authors:  Nicholas CR, Wang JB, Coker A, Mitchell JM, Klaire SS, Yazar-Klosinski B, Emerson A, Brown RT, Doblin R