PRIMARY STUDY

Endocannabinoid signalling modulates susceptibility to traumatic stress exposure

Key Findings:  These data indicate amygdala 2-AG signalling mechanisms promote resilience to adverse effects of acute traumatic stress and facilitate adaptation to repeated stress exposure.

Type of Study:  Animal Study

Study Result:  Positive

Research Location(s):  United States

Year of Pub:  2017


Cannabinoids Studied:  2-Arachidonoyl Glycerol (2-AG)

Phytocannabinoid Source:  Not Applicable

Receptors Studied:  CB1




Citation:  Bluett RJ, et al. Endocannabinoid signalling modulates susceptibility to traumatic stress exposure. Nat Commun. 2017; 8:14782. doi: 10.1038/ncomms14782

Authors:  Bluett RJ, Báldi R, Haymer A, Gaulden AD, Hartley ND, Parrish WP, Baechle J, Marcus DJ, Mardam-Bey R, Shonesy BC, Uddin MJ, Marnett LJ, Mackie K, Colbran RJ, Winder DG, Patel S