PRIMARY STUDY

The endogenous cannabinoid system controls extinction of aversive memories

Key Findings:  Results of this study led the researchers to posit that endocannabinoids facilitate extinction of aversive memories through their selective inhibitory effects on local inhibitory networks in the amygdala.

Type of Study:  Animal Study

Study Result:  Positive

Research Location(s):  Germany

Year of Pub:  2002


Cannabinoids Studied:  SR-x Synthetic Cannabinoids

Phytocannabinoid Source:  Not Applicable

Receptors Studied:  CB1

Ligands Studied:  GABA




Citation:  Marsicano G, et al. The endogenous cannabinoid system controls extinction of aversive memories. Nature. 2002; 418:530-4. doi: 10.1038/nature00839

Authors:  Marsicano G, Wotjak CT, Azad SC, Bisogno T, Rammes G, Cascio MG, Hermann H, Tang J, Hofmann C, Zieglgänsberger W, Di Marzo V, Lutz B