PRIMARY STUDY
Cannabis sativa L. Extract Alleviates Neuropathic Pain and Modulates CB1 and CB2 Receptor Expression in Rat
Key Findings: This study found that Cannabis sativa L. extracts demonstrated antinociceptive effects comparable to gabapentin in alleviating neuropathic pain in rats, with changes in CB1 and CB2 receptor expression suggesting additional signaling pathways may contribute to pain modulation.
Type of Study: Animal Study
Study Sample Size: 130
Study Result: Positive
Research Location(s): Poland
Year of Pub: 2024
Cannabinoids Studied: Cannabidiol (CBD)
Phytocannabinoid Source: Hemp derived
Citation: Bartkowiak-Wieczorek J, et al. Cannabis sativa L. Extract Alleviates Neuropathic Pain and Modulates CB1 and CB2 Receptor Expression in Rat. Biomolecules. 2024; 14:(unknown pages). doi: 10.3390/biom14091065
Authors: Bartkowiak-Wieczorek J, Bienert A, Czora-Poczwardowska K, Kujawski R, Szulc M, Mikołajczak P, Wizner AM, Jamka M, Hołysz M, Wielgus K, Słomski R, Mądry E
