PRIMARY STUDY

Cannabinoids as a Natural Alternative for the Management of Neuropathic Pain: A Systematic Review of Randomized Placebo-Controlled Trials

Key Findings:  This systematic review finds that cannabinoids provided significant relief from chronic pain, compared to placebo. Transdermal cannabidiol (CBD) leads to a more pronounced reduction in sharp pain. Minimal to no side effects were recorded.

Type of Study:  Clinical Meta-analysis

Study Sample Size:  5

Study Result:  Positive

Research Location(s):  Mauritius

Year of Pub:  2024


Cannabinoids Studied:  Cannabidiol (CBD), Tetrahydrocannabinol (THC), Cannabinoid (unspecified)

Phytocannabinoid Source:  Unspecified

Route of Administration:  Oral (Ingestion), Sublingual/Oromucosal

Cannabinoid Ratio:  (THC : CBD)   0 : 0    

Clinical Relevance:  Cannabinoids provide significant relief from chronic pain.

Adverse Events:  Minimal to no side effects were recorded.




Citation:  Reechaye D, et al. Cannabinoids as a Natural Alternative for the Management of Neuropathic Pain: A Systematic Review of Randomized Placebo-Controlled Trials. Cureus. 2024; 16:e70021. doi: 10.7759/cureus.70021

Authors:  Reechaye D, Perrine ALA, Jahajeeah Y, Dookhee F, Robinson J, Banerjee I