Key Findings:  This systematic review finds that cannabinoids provided significant relief from chronic pain, compared to placebo. Transdermal cannabidiol (CBD) leads to a more pronounced reduction in sharp pain. Minimal to no side effects were recorded.
Type of Study:  Clinical Meta-analysis
Study Sample Size:  5
Study Result:  Positive
Research Location(s):  Mauritius
Year of Pub:  2024
Cannabinoids Studied:  Cannabidiol (CBD), Tetrahydrocannabinol (THC), Cannabinoid (unspecified)
Phytocannabinoid Source:  Unspecified
Route of Administration:  Oral (Ingestion), Sublingual/Oromucosal
Cannabinoid Ratio:  (THC : CBD)   0 : 0    
Clinical Relevance:  Cannabinoids provide significant relief from chronic pain.
Adverse Events:  Minimal to no side effects were recorded.
Citation:  Reechaye D, et al. Cannabinoids as a Natural Alternative for the Management of Neuropathic Pain: A Systematic Review of Randomized Placebo-Controlled Trials. Cureus. 2024; 16:e70021. doi: 10.7759/cureus.70021
Authors:  Reechaye D, Perrine ALA, Jahajeeah Y, Dookhee F, Robinson J, Banerjee I