PRIMARY STUDY
Placebo Response and Media Attention in Randomized Clinical Trials Assessing Cannabis-Based Therapies for Pain: A Systematic Review and Meta-analysis
Key Findings: When looking at randomized clinical trials on the effects of cannabinoids compared with placebo for treating pain, this analysis finds that placebo contributed significantly to pain reduction. Theories as to why include the media attention and preconceived opinions on the potential pain-relieving effects of cannabinoids.
Type of Study: Clinical Meta-analysis
Study Sample Size: 1459
Study Result: Inconclusive
Research Location(s): Sweden
Year of Pub: 2022
Cannabinoids Studied: Cannabidiol (CBD), Tetrahydrocannabinol (THC), Pharma THC, Pharma THC:CBD
Phytocannabinoid Source: Unspecified
Chemotype: Chemotype I, Chemotype II
Route of Administration: Inhalation, Oral (Ingestion), Sublingual/Oromucosal
Citation: Gedin F, et al. Placebo Response and Media Attention in Randomized Clinical Trials Assessing Cannabis-Based Therapies for Pain: A Systematic Review and Meta-analysis. JAMA Netw Open. 2022; 5:e2243848. doi: 10.1001/jamanetworkopen.2022.43848
Authors: Gedin F, Blomé S, Pontén M, Lalouni M, Fust J, Raquette A, Vadenmark Lundquist V, Thompson WH, Jensen K
