PRIMARY STUDY

Palmitoylethanolamide in the Treatment of Chronic Pain: A Systematic Review and Meta-Analysis of Double-Blind Randomized Controlled Trials

Key Findings:  The findings of this systematic review and meta-analysis support that palmitoylethanolamide (PEA) is a potential treatment for chronic pain. Studies found PEA to be overall effective and well-tolerated.

Type of Study:  Clinical Meta-analysis

Study Sample Size:  11

Study Result:  Positive

Research Location(s):  Austria, Canada

Year of Pub:  2023


Cannabinoids Studied:  Anandamide (AEA), Palmitoylethanolamide (PEA)

Phytocannabinoid Source:  Not Applicable

Receptors Studied:  CB1, CB2, TRPV1, PPAR - Alpha




Citation:  Lang-Illievich K, et al. Palmitoylethanolamide in the Treatment of Chronic Pain: A Systematic Review and Meta-Analysis of Double-Blind Randomized Controlled Trials. Nutrients. 2023; 15:(unknown pages). doi: 10.3390/nu15061350

Authors:  Lang-Illievich K, Klivinyi C, Lasser C, Brenna CTA, Szilagyi IS, Bornemann-Cimenti H