PRIMARY STUDY
Effectiveness and Safety of Cannabinoids as an Add-On Therapy in the Treatment of Resistant Spasticity in Multiple Sclerosis: A Systematic Review
Key Findings: According to this systematic review, adding THC:CBD spray was more effective in treating multiple sclerosis spasticity than optimizing first-line antispastic drugs in selected patients. The safety and tolerability profiles align with previous trials.
Type of Study: Meta-analysis
Study Sample Size: 5
Study Result: Positive
Research Location(s): Spain
Year of Pub: 2023
Cannabinoids Studied: Cannabidiol (CBD), Tetrahydrocannabinol (THC), Pharma THC:CBD
Phytocannabinoid Source: Unspecified
Route of Administration: Sublingual/Oromucosal
Citation: Martinez-Paz C, et al. Effectiveness and Safety of Cannabinoids as an Add-On Therapy in the Treatment of Resistant Spasticity in Multiple Sclerosis: A Systematic Review. Cannabis Cannabinoid Res. 2023; 8:580-588. doi: 10.1089/can.2022.0254
Authors: Martinez-Paz C, García-Cabrera E, Vilches-Arenas Á
