Key Findings:  This study measured the oral bioavailability of β-Caryophyllene (BCP) in a self-emulsifying drug delivery system (SEDDS) when given to healthy subjects. It was deemed safe and well-tolerated, and the SEDDS system effectively increased the bioavailability BCP.
Type of Study:  Double Blind Clinical Trial
Study Sample Size:  24
Study Result:  Positive
Study Location(s):  Germany, Switzerland, United States
Year of Pub:  2022
Cannabinoids Studied:  Cannabidiol (CBD), Tetrahydrocannabinol (THC)
Phytocannabinoid Source:  Not Applicable
Terpenes Studied:  ß-Caryophyllene
Receptors Studied:  CB1, CB2, PPAR - Alpha, PPAR - Gamma, PPARs
Ligands Studied:  Serotonin