PRIMARY STUDY
Anti-cancer potential of cannabis terpenes in a Taxol-resistant model of breast cancer
Key Findings: In this in vitro study of chemotherapy-resistant breast cancer cells, cannabis and specific terpenes and flavinoids had anti-cancer effects alone and when combined. This may lead to the development of novel therapies in the treatment of resistant breast cancers. Nerolidol and β-caryophyllene had the most significant effect.
Type of Study: Laboratory Study
Study Result: Positive
Research Location(s): Canada
Year of Pub: 2022
Cannabinoids Studied: Cannabidiol (CBD), Tetrahydrocannabinol (THC), Cannabinoid (unspecified)
Phytocannabinoid Source: Unspecified
Terpenes Studied: ß-Caryophyllene, Myrcene, Nerolidol, Ocimene, Terpinolene
Route of Administration: In vitro
Citation: Tomko AM, et al. Anti-cancer potential of cannabis terpenes in a Taxol-resistant model of breast cancer. Can J Physiol Pharmacol. 2022; 100:806-817. doi: 10.1139/cjpp-2021-0792
Authors: Tomko AM, Whynot EG, O'Leary LF, Dupré DJ
