PRIMARY STUDY

Essential Oil from the Leaves of Chromolaena odorata, and Sesquiterpene Caryophyllene Oxide Induce Sedative Activity in Mice

Key Findings:  This study found that caryophyllene oxide causes significant depression of the central nervous system (CNS) in mice in this model of insomnia and CNS-related disorders.

Type of Study:  Animal Study

Study Result:  Inconclusive

Research Location(s):  Japan

Year of Pub:  2021


Cannabinoids Studied:  Other Related Compounds

Phytocannabinoid Source:  Not Applicable

Terpenes Studied:  ß-Caryophyllene

Ligands Studied:  GABA




Citation:  Dougnon G and Ito M. Essential Oil from the Leaves of Chromolaena odorata, and Sesquiterpene Caryophyllene Oxide Induce Sedative Activity in Mice. Pharmaceuticals (Basel). 2021; 14:(unknown pages). doi: 10.3390/ph14070651

Authors:  Dougnon G, Ito M