PRIMARY STUDY
Myrtenal and β-caryophyllene oxide screened from Liquidambaris Fructus suppress NLRP3 inflammasome components in rheumatoid arthritis
Key Findings: Myrtenal and β-caryophyllene oxide, used in a petroleum ether extract of Liquidambaris Fructus in this experiment, showed the potential to suppress NLRP3 inflammasome activation, potentially leading to therapeutic uses in the treatment of inflammatory symptoms related to conditions like rheumatoid arthritis.
Type of Study: Animal Study
Study Sample Size: 36
Study Result: Positive
Research Location(s): China
Year of Pub: 2021
Cannabinoids Studied: Other Related Compounds
Phytocannabinoid Source: Not Applicable
Terpenes Studied: ß-Caryophyllene
Ligands Studied: Pro-inflammatory cytokines
Route of Administration: Oral (Ingestion)
Citation: Li WX, et al. Myrtenal and β-caryophyllene oxide screened from Liquidambaris Fructus suppress NLRP3 inflammasome components in rheumatoid arthritis. BMC Complement Med Ther. 2021; 21:242. doi: 10.1186/s12906-021-03410-2
Authors: Li WX, Qian P, Guo YT, Gu L, Jurat J, Bai Y, Zhang DF
