PRIMARY STUDY
β-Caryophyllene suppresses ferroptosis induced by cerebral ischemia reperfusion via activation of the NRF2/HO-1 signaling pathway in MCAO/R rats
Key Findings: Via its role in ferroptosis regulation β-Caryophyllene (BCP) showed neuroprotective effects in this animal model of ischemic stroke.
Type of Study: Animal Study
Study Result: Positive
Research Location(s): China
Year of Pub: 2022
Cannabinoids Studied:
Phytocannabinoid Source: Unspecified
Terpenes Studied: ß-Caryophyllene
Route of Administration: In vitro
Citation: Hu Q, et al. β-Caryophyllene suppresses ferroptosis induced by cerebral ischemia reperfusion via activation of the NRF2/HO-1 signaling pathway in MCAO/R rats. Phytomedicine. 2022; 102:154112. doi: 10.1016/j.phymed.2022.154112
Authors: Hu Q, Zuo T, Deng L, Chen S, Yu W, Liu S, Liu J, Wang X, Fan X, Dong Z
