PRIMARY STUDY

Anti-neuropathic pain mechanistic study of A. conyzoides essential oil, Precocene II, Caryophyllene, or Longifolene as single agent and in combination with pregabalin

Key Findings:  The authors conclude that A. conyzoides essential oil and caryophyllene may represent novel drugs to treat neuropathic pain.

Type of Study:  Animal Study

Study Result:  Positive

Research Location(s):  Indonesia

Year of Pub:  2022


Cannabinoids Studied: 

Phytocannabinoid Source:  Not Applicable

Terpenes Studied:  ß-Caryophyllene

Ligands Studied:  GABA




Citation:  Sukmawan YP, et al. Anti-neuropathic Pain Mechanistic Study on A. conyzoides Essential Oil, Precocene II, Caryophyllene, or Longifolene as Single Agents and in Combination with Pregabalin. CNS Neurol Disord Drug Targets. 2023; 22:924-931. doi: 10.2174/1871527321666220418121329

Authors:  Sukmawan YP, Anggadiredja K, Adnyana IK