PRIMARY STUDY
Anti-Inflammatory Effect of Beta-Caryophyllene Mediated by the Involvement of TRPV1, BDNF and trkB in the Rat Cerebral Cortex after Hypoperfusion/Reperfusion
Key Findings: REsulting data revealed that beta-caryophyllene modulates early events of cerebral inflammation triggered by the bilateral common carotid artery occlusion followed by reperfusion via the regulation of TRPV1 and the BDNF-trkB system.
Type of Study: Animal Study
Study Result: Positive
Research Location(s): Italy
Year of Pub: 2022
Cannabinoids Studied:
Phytocannabinoid Source: Not Applicable
Terpenes Studied: ß-Caryophyllene
Receptors Studied: TRPV1
Ligands Studied: Anti-inflammatory cytokines, Pro-inflammatory cytokines
Citation: Serra MP, et al. Anti-Inflammatory Effect of Beta-Caryophyllene Mediated by the Involvement of TRPV1, BDNF and trkB in the Rat Cerebral Cortex after Hypoperfusion/Reperfusion. Int J Mol Sci. 2022; 23:(unknown pages). doi: 10.3390/ijms23073633
Authors: Serra MP, Boi M, Carta A, Murru E, Carta G, Banni S, Quartu M
