PRIMARY STUDY
RIFM fragrance ingredient safety assessment, β-caryophyllene, CAS Registry Number 87-44-5
Key Findings: There are no safety concerns for β-caryophyllene for skin sensitization under the current declared levels of use. β-caryophyllene is not genotoxic.
Type of Study: Meta-analysis
Study Result: Inconclusive
Research Location(s): Brazil, Germany, Japan, Sweden, United States
Year of Pub: 2022
Cannabinoids Studied:
Phytocannabinoid Source: Not Applicable
Terpenes Studied: ß-Caryophyllene
Citation: Api AM, et al. RIFM fragrance ingredient safety assessment, β-caryophyllene, CAS Registry Number 87-44-5. Food Chem Toxicol. 2022; 159 Suppl 1:112707. doi: 10.1016/j.fct.2021.112707
Authors: Api AM, Belsito D, Botelho D, Bruze M, Burton GA, Buschmann J, Cancellieri MA, Dagli ML, Date M, Dekant W, Deodhar C, Fryer AD, Jones L, Joshi K, Kumar M, Lapczynski A, Lavelle M, Lee I, Liebler DC, Moustakas H, Na M, Penning TM, Ritacco G, Romine J, Sadekar N, Schultz TW, Selechnik D, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, Tokura Y
