PRIMARY STUDY
Beta-caryophyllene attenuates short-term recurrent seizure activity and blood-brain-barrier breakdown after pilocarpine-induced status epilepticus in rats
Key Findings: Data showed that animals treated with beta-caryophyllene (100 mg/kg, ip) presented with fewer seizure activities than vehicle-treated counterparts.
Type of Study: Animal Study
Study Result: Positive
Research Location(s): Brazil
Year of Pub: 2022
Cannabinoids Studied:
Phytocannabinoid Source: Not Applicable
Terpenes Studied: ß-Caryophyllene
Citation: Mallmann MP, et al. Beta-caryophyllene attenuates short-term recurrent seizure activity and blood-brain-barrier breakdown after pilocarpine-induced status epilepticus in rats. Brain Res. 2022; 1784:147883. doi: 10.1016/j.brainres.2022.147883
Authors: Mallmann MP, Mello FK, Neuberger B, da Costa Sobral KG, Fighera MR, Royes LFF, Furian AF, Oliveira MS
