PRIMARY STUDY

Analgesic Potential of Terpenes Derived from Cannabis sativa

Key Findings:  This review discusses the current knowledge of cannabis terpenes in both human and animal research. Although large sample and human-controlled trials are limited, there appears to be potential therapeutic use in pain management with relative safety with few side effects and toxicities reported.

Type of Study:  Meta-analysis

Study Result:  Positive

Study Location(s):  United States

Year of Pub:  2021


Cannabinoids Studied:  Cannabidiol (CBD), Tetrahydrocannabinol (THC), Cannabinoid (unspecified)

Phytocannabinoid Source:  Unspecified

Terpenes Studied:  ß-Caryophyllene, Camphene, Eucalyptol, Geraniol, Humulene, Limonene, Linalool, Myrcene, Nerolidol, Ocimene, Pinene, Terpineol, Terpinolene

Receptors Studied:  CB1, CB2, GPCR 55, TRPA1, TRPV1, GPCR, TRPs

Ligands Studied:  Anti-inflammatory cytokines, Dopamine, Norepinephrine, Pro-inflammatory cytokines