Key Findings:  Piper purusanum essential oil containing β-caryophyllene (>57%) and α-humulene (>14%) inhibited egg hatching, caused larval death, inhibited the action of acetylcholinesterase while showing no lethal effect on non-target aquatic animals (e.g., Toxorhynchites splendens, Anisops bouvieri, Gambusia affinis, and Diplonychus indicus).
Type of Study:  Animal Study
Study Result:  Positive
Research Location(s):  Brazil
Year of Pub:  2022
Cannabinoids Studied: 
Phytocannabinoid Source:  Not Applicable
Terpenes Studied:  ß-Caryophyllene, Humulene
Citation:  de Oliveira AC, et al. Essential oil of Piper purusanum C.DC (Piperaceae) and its main sesquiterpenes: biodefensives against malaria and dengue vectors, without lethal effect on non-target aquatic fauna. Environ Sci Pollut Res Int. 2022; 29:47242-47253. doi: 10.1007/s11356-022-19196-w
Authors:  de Oliveira AC, Simões RC, Lima CAP, da Silva FMA, Nunomura SM, Roque RA, Tadei WP, Nunomura RCS