RELATED STUDY

Cannabinoids, Endocannabinoids, and Related Analogs in Inflammation

Key Findings:  A large body of preclinical data on all classes of cannabinoids, including the endogenous examples, point to a variety of therapeutic targets for cannabinoids and important roles for the endocannabinoids in the physiology of inflammation.

Type of Study:  Meta-analysis

Study Result:  Positive

Research Location(s):  United States

Year of Pub:  2009


Cannabinoids Studied:  Cannabichromene (CBC), Cannabidiol (CBD), Tetrahydrocannabinol (THC), CP-x Synthetic Cannabinoids, AM-x Synthetic Cannabinoids, SR-x Synthetic Cannabinoids, WIN-x Synthetic Cannabinoids, Anandamide (AEA), Fatty Acid Amide Hydrolase (FAAH), 2-Arachidonoyl Glycerol (2-AG), Monoacylglycerol Lipase (MAGL), Other Related Compounds

Phytocannabinoid Source:  Not Applicable

Terpenes Studied:  ß-Caryophyllene

Receptors Studied:  CB1, CB2, GPCR 55, PPAR - Gamma, PPARs

Ligands Studied:  Anti-inflammatory cytokines, Pro-inflammatory cytokines




Citation:  Burstein SH and Zurier RB. Cannabinoids, endocannabinoids, and related analogs in inflammation. AAPS J. 2009; 11:109-19. doi: 10.1208/s12248-009-9084-5

Authors:  Burstein SH, Zurier RB