PRIMARY STUDY

β-Caryophyllene induces apoptosis and inhibits cell proliferation by deregulation of STAT-3/mTOR/AKT signaling in human bladder cancer cells: An in vitro study

Key Findings:  Resulting data revealed led the authors to posit that BCP is an effective treatment against bladder cancer (i.e. BC T24 and 5637 cells).

Type of Study:  Laboratory Study

Study Result:  Positive

Research Location(s):  China

Year of Pub:  2021


Cannabinoids Studied: 

Phytocannabinoid Source:  Not Applicable

Terpenes Studied:  ß-Caryophyllene

Route of Administration:  In vitro




Citation:  Yu X, et al. β-Caryophyllene induces apoptosis and inhibits cell proliferation by deregulation of STAT-3/mTOR/AKT signaling in human bladder cancer cells: An in vitro study. J Biochem Mol Toxicol. 2021; 35:e22863. doi: 10.1002/jbt.22863

Authors:  Yu X, Liao B, Zhu P, Cheng S, Du Z, Jiang G