PRIMARY STUDY
Caryophyllene Oxide, the Active Compound Isolated from Leaves of Hymenaea courbaril L. (Fabaceae) with Antiproliferative and Apoptotic Effects on PC-3 Androgen-Independent Prostate Cancer Cell Line
Key Findings: Resulting data found that caryophyllene oxide, induced early and late apoptosis, against PC-3 cells. As such, the authors posit that caryophyllene oxide is a safe anti-proliferative agent against PC-3 cells, with low toxicity towards normal cells.
Type of Study: Laboratory Study
Study Result: Positive
Research Location(s): Colombia
Year of Pub: 2021
Cannabinoids Studied:
Phytocannabinoid Source: Not Applicable
Terpenes Studied: ß-Caryophyllene
Route of Administration: In vitro
Citation: Delgado C, et al. Caryophyllene Oxide, the Active Compound Isolated from Leaves of Hymenaea courbaril L. (Fabaceae) with Antiproliferative and Apoptotic Effects on PC-3 Androgen-Independent Prostate Cancer Cell Line. Molecules. 2021; 26:(unknown pages). doi: 10.3390/molecules26206142
Authors: Delgado C, Mendez-Callejas G, Celis C
