Key Findings:  A team of physicians treated two female patients, whose painful leg ulcers failed to respond to all available best practices, with topical cannabis containing cannabinoids [THC (<1 mg/mL) and CBD (3.75 mg/mL) at a ~1:4 ratio], terpenes (beta-carophyllene), and flavonoids (quercetin, disomin, hersperidin). After an average of 76 days wounds closure was achieved in both patients with no adverse reactions. Additionally, after an average of of 63 days neither patient requirred any other analgesics
Type of Study:  Clinical Trial
Study Sample Size:  2
Study Result:  Positive
Study Location(s):  Canada
Year of Pub:  2020
Cannabinoids Studied:  Cannabidiol (CBD), Tetrahydrocannabinol (THC)
Phytocannabinoid Source:  Cannabis Flower derived
Chemotype:  Chemotype II
Terpenes Studied:  ß-Caryophyllene
Sub-Ratio: THC:CBD at a ~1:4 ratio
Dosage: THC (<1 mg/mL) and CBD (3.75 mg/mL)
Route of Administration:  Topical