PRIMARY STUDY
β-Caryophyllene, a natural bicyclic sesquiterpene attenuates β-adrenergic agonist-induced myocardial injury in a cannabinoid receptor-2 dependent and independent manner
Key Findings: Resulting data showed that the administration of BCP induced significant cardio-protective effects in a CB2-dependent and independent manner.
Type of Study: Animal Study
Study Result: Positive
Research Location(s): United Arab Emirates
Year of Pub: 2021
Cannabinoids Studied:
Phytocannabinoid Source: Not Applicable
Terpenes Studied: ß-Caryophyllene
Receptors Studied: CB2
Ligands Studied: Anti-inflammatory cytokines, Pro-inflammatory cytokines
Route of Administration: Oral (Ingestion)
Citation: Meeran MFN, et al. β-Caryophyllene, a natural bicyclic sesquiterpene attenuates β-adrenergic agonist-induced myocardial injury in a cannabinoid receptor-2 dependent and independent manner. Free Radic Biol Med. 2021; 167:348-366. doi: 10.1016/j.freeradbiomed.2021.01.046
Authors: Meeran MFN, Laham F, Azimullah S, Sharma C, Al Kaabi AJ, Tariq S, Adeghate E, Goyal SN, Ojha S
