PRIMARY STUDY

Anticonvulsant, Anxiolytic and Antidepressant Properties of the β-caryophyllene in Swiss Mice: Involvement of Benzodiazepine-GABAAergic, Serotonergic and Nitrergic Systems

Key Findings:  Data lends additional support in understanding the neuromolecular mechanisms underlying the anxiolytic, antidepressant and anticonvulsive properties of β-caryophyllene.

Type of Study:  Animal Study

Study Result:  Positive

Research Location(s):  Brazil

Year of Pub:  2021


Cannabinoids Studied: 

Phytocannabinoid Source:  Unspecified

Terpenes Studied:  ß-Caryophyllene

Ligands Studied:  GABA, Serotonin




Citation:  da Silva Oliveira GL, et al. Anticonvulsant, Anxiolytic and Antidepressant Properties of the β-caryophyllene in Swiss Mice: Involvement of Benzodiazepine-GABAAergic, Serotonergic and Nitrergic Systems. Curr Mol Pharmacol. 2021; 14:36-51. doi: 10.2174/1874467213666200510004622

Authors:  da Silva Oliveira GL, da Silva JCCL, Dos Santos C L da Silva AP, Feitosa CM, de Castro Almeida FR