PRIMARY STUDY

β-caryophyllene, a dietary phytocannabinoid attenuates oxidative stress, inflammation, apoptosis and prevents structural alterations of the myocardium against doxorubicin-induced acute cardiotoxicity in rats: An in vitro and in vivo study

Key Findings:  Treatment with BCP showed significant cardioprotective effects against doxorubicin-induced acute cardiotoxicity.

Type of Study:  Animal Study

Study Result:  Positive

Research Location(s):  United Arab Emirates

Year of Pub:  2019


Cannabinoids Studied: 

Phytocannabinoid Source:  Not Applicable

Terpenes Studied:  ß-Caryophyllene

Route of Administration:  Injection




Citation:  Al-Taee H, et al. β-caryophyllene, a dietary phytocannabinoid attenuates oxidative stress, inflammation, apoptosis and prevents structural alterations of the myocardium against doxorubicin-induced acute cardiotoxicity in rats: An in vitro and in vivo study. Eur J Pharmacol. 2019; 858:172467. doi: 10.1016/j.ejphar.2019.172467

Authors:  Al-Taee H, Azimullah S, Meeran MFN, Alaraj Almheiri MK, Al Jasmi RA, Tariq S, Ab Khan M, Adeghate E, Ojha S