PRIMARY STUDY

Effects of Cannabidiol and Beta-Caryophyllene Alone or in Combination in a Mouse Model of Permanent Ischemia

Key Findings:  Resulting data revealed that treatment with Beta-Caryophyllene (BCP), CBD, and their combination was associated with a significant decrease in infarct size.

Type of Study:  Animal Study

Study Result:  Positive

Research Location(s):  United States

Year of Pub:  2021


Cannabinoids Studied:  Cannabidiol (CBD)

Phytocannabinoid Source:  Unspecified

Chemotype:  Chemotype III

Terpenes Studied:  ß-Caryophyllene

Receptors Studied:  CB2

Dosage: Beta-Caryophyllene (BCP) (3–30 mg/kg IP) and CBD (3–30 mg/kg IP), given alone or in combination (30:3, 30:10, and 30:30 BCP:CBD)

Route of Administration:  Injection




Citation:  Yokubaitis CG, et al. Effects of Cannabidiol and Beta-Caryophyllene Alone or in Combination in a Mouse Model of Permanent Ischemia. Int J Mol Sci. 2021; 22:(unknown pages). doi: 10.3390/ijms22062866

Authors:  Yokubaitis CG, Jessani HN, Li H, Amodea AK, Ward SJ