PRIMARY STUDY
β-Caryophyllene exerts protective antioxidant effects through the activation of NQO1 in the MPTP model of Parkinson's disease
Key Findings: β-caryophyllene (BCP) protects dopaminergic neurons from neuronal death by at least partially inducing antioxidant effects via the augmentation of NAD(P)H quinone oxidoreductase activity.
Type of Study: Animal Study
Study Result: Positive
Research Location(s): Mexico
Year of Pub: 2021
Cannabinoids Studied:
Phytocannabinoid Source: Unspecified
Terpenes Studied: ß-Caryophyllene
Receptors Studied: CB2
Ligands Studied: Dopamine
Route of Administration: Injection
Citation: Flores-Soto ME, et al. β-Caryophyllene exerts protective antioxidant effects through the activation of NQO1 in the MPTP model of Parkinson's disease. Neurosci Lett. 2021; 742:135534. doi: 10.1016/j.neulet.2020.135534
Authors: Flores-Soto ME, Corona-Angeles JA, Tejeda-Martinez AR, Flores-Guzman PA, Luna-Mujica I, Chaparro-Huerta V, Viveros-Paredes JM
