PRIMARY STUDY
Beta-caryophyllene Is A Dietary Cannabinoid
Key Findings: Activation of the CB(2) receptor is a potential therapeutic strategy for the treatment of inflammation, pain, atherosclerosis, and osteoporosis. Here, we report that the widespread plant volatile (E)-beta-caryophyllene [(E)-BCP] selectively binds to the CB(2) receptor and that it is a functional CB(2) agonist.
Type of Study: Animal Study
Study Result: Positive
Research Location(s): Germany, Italy, Switzerland, United States
Year of Pub: 2008
Cannabinoids Studied:
Phytocannabinoid Source: Not Applicable
Terpenes Studied: ß-Caryophyllene
Receptors Studied: CB2
Citation: Gertsch J, et al. Beta-caryophyllene is a dietary cannabinoid. Proc Natl Acad Sci U S A. 2008; 105:9099-104. doi: 10.1073/pnas.0803601105
Authors: Gertsch J, Leonti M, Raduner S, Racz I, Chen JZ, Xie XQ, Altmann KH, Karsak M, Zimmer A
