PRIMARY STUDY
β-Caryophyllene, A CB2 Receptor Agonist Produces Multiple Behavioral Changes Relevant To Anxiety And Depression In Mice
Key Findings: Taken together, these preclinical results suggest that CB2 receptors may provide alternative therapeutic targets for the treatment of anxiety (anti-compulsive-like effect) and depression.
Type of Study: Animal Study
Study Result: Positive
Research Location(s): United Arab Emirates
Year of Pub: 2014
Cannabinoids Studied: AM-x Synthetic Cannabinoids
Phytocannabinoid Source: Not Applicable
Terpenes Studied: ß-Caryophyllene
Receptors Studied: CB2
DOSING DETAILS 
Study Dosing Objective: Effective Dose
Established Protocol: Effective dose
Dosing Regimen: β-caryophyllene (BCP) 50mg/kg
Starting Dose: BCP 50mg/kg
Maximum Dose: BCP 50mg/kg
Additional Notes: Pharmacodynamic Study Data
Citation: Bahi A, et al. β-Caryophyllene, a CB2 receptor agonist produces multiple behavioral changes relevant to anxiety and depression in mice. Physiol Behav. 2014; 135:119-24. doi: 10.1016/j.physbeh.2014.06.003
Authors: Bahi A, Al Mansouri S, Al Memari E, Al Ameri M, Nurulain SM, Ojha S
