PRIMARY STUDY
Synergistic Interaction of β-Caryophyllene With Aromadendrene Oxide 2 and Phytol Induces Apoptosis on Skin Epidermoid Cancer Cells
Key Findings: The present study demonstrates interactions among β-C, AO-(2) and P in the induction of apoptosis on A431 and HaCaT cells. These data suggest the combination of β-caryophyllene with aromadendrene oxide 2 and phytol could be potential therapeutics for the treatment of skin epidermoid cancer and precancerous cells.
Type of Study: Laboratory Study
Study Result: Positive
Research Location(s): India
Year of Pub: 2018
Cannabinoids Studied:
Phytocannabinoid Source: Not Applicable
Terpenes Studied: ß-Caryophyllene, Phytol
Route of Administration: Topical
Citation: Pavithra PS, et al. Synergistic interaction of β-caryophyllene with aromadendrene oxide 2 and phytol induces apoptosis on skin epidermoid cancer cells. Phytomedicine. 2018; 47:121-134. doi: 10.1016/j.phymed.2018.05.001
Authors: Pavithra PS, Mehta A, Verma RS
