Key Findings:  The results show significant ability of humulene and especially of beta-caryophyllene oxide to enhance the anti-proliferative effects of FU and OxPt in cancer cell lines Caco-2 and SW-620.
Type of Study:  Laboratory Study
Study Result:  Positive
Research Location(s):  Czech Republic
Year of Pub:  2019
Cannabinoids Studied: 
Phytocannabinoid Source:  Not Applicable
Terpenes Studied:  ß-Caryophyllene, Humulene
Route of Administration:  In vitro
Citation:  Ambrož M, et al. Sesquiterpenes α-humulene and β-caryophyllene oxide enhance the efficacy of 5-fluorouracil and oxaliplatin in colon cancer cells. Acta Pharm. 2019; 69:121-128. doi: 10.2478/acph-2019-0003
Authors:  Ambrož M, Šmatová M, Šadibolová M, Pospíšilová E, Hadravská P, Kašparová M, Skarková VH, Králová V, Skálová L